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上海张江转化医学研发中心科研论文专辑

上海宝藤在精准医学领域实现了跨越式发展,在建设面向精准医学应用的国际化 先进技术中心、国际高端的临床医学检验机构的同时,打造了以精准医学大师 工作室及精准医学示范应用网络为依托的张江国家级创新示范区精准医学大数 据中心。先后与中国医学科学院分子肿瘤国家重点实验室、复旦大学、 第二军医大学等合作先后获批了科技部重大专项、863项目“生物大数据应用关 键技术研究”,共建“上海张江国家创新示范区精准医学大数据公共服务平台” 及“上海精准医疗大数据中心”等,并在政府主导下,建立了海外高科技园区。 与合作单位的项目成果已在《Nature》,《Nat Biotechnol》, 《Cancer Res》, 《Nat Commun》, 《Proc Natl Acad Sci U S A》, 《Cancer Cell》, 《Immunity》等国际主流杂志发表18篇SCI论著,累积影响因子达190.97, 最高影响因子为41.514。

文章目录(SCI收录)

  • Gao Y, Zhu Y, Zhang Z, Zhang C, Huang X, Yuan Z. Clinical significance of pancreatic circulating tumor cells using combined negative enrichment and immunostaining-fluorescence in situ hybridization. J Exp Clin Cancer Res. 2016 Apr 12;35(1):66. IF=4.429
  • Gao S, Zhou F, Zhao C, Ma Z, Jia R, Liang S, Zhang M, Zhu X, Zhang P, Wang L, Su F, Zhao J, Liu G, Peng B, Feng X. Gastric cardia adenocarcinoma microRNA profiling in Chinese patients. Tumour Biol. 2016 Jan 18. IF=3.611
  • Yuan Sheng, Ting Wang, Hengyu Li, Zhenzhen Zhang, Jianghao Chen, Chenyang He, Yongping Li, Yonggang Lv, Juliang Zhang, Cheng Xu, Zhen Wan, Chen Huang and Ling Wang. Comparison of analytic performances of Cellsearch and iFISH approach in detecting cirtulating tumor cells. Oncotarget. 2015. Dec. 19; 6: DOI: 10.18632/oncotarget.6688. IF=6.359
  • He Q, Peng B, Zhuang D, Xiao L, Zheng L, Fan Z, Zhu J, Xu B, Xu C, Zhao J, Wu L, Zhou P, Hou L, Yu F, Zhao G. Clinicopathological significance of β -tubulin isotype III gene expression in breast cancer patients. Cancer Biomark. 2015 Nov 24;15(6):823-31. doi: 10.3233/CBM-150526. IF=1.721
  • Peifer M, Hertwig F, Roels F, Dreidax D, Gartlgruber M, Menon R, Krämer A, Roncaioli JL, Sand F, Heuckmann JM, Ikram F, Schmidt R, Ackermann S, Engesser A, Kahlert Y, Vogel W, Altmüller J, Nürnberg P, Thierry-Mieg J, Thierry-Mieg D, Mariappan A, Heynck S, Mariotti E, Henrich KO, Gloeckner C, Bosco G, Leuschner I, Schweiger MR, Savelyeva L, Watkins SC, Shao C, Bell E, Höfer T, Achter V, Lang U, Theissen J, Volland R, Saadati M, Eggert A, de Wilde B, Berthold F, Peng Z, Zhao C, Shi L, Ortmann M, Büttner R, Perner S, Hero B, Schramm A, Schulte JH, Herrmann C, O'Sullivan RJ, Westermann F, Thomas RK, Fischer M. Telomerase activation by genomic rearrangements in high-risk neuroblastoma. Nature. 2015 Oct 29;526(7575):700-4. doi: 10.1038/nature14980. Epub 2015 Oct 14. IF=41.456
  • Li S, Wang L, Ma Z, Ma Y, Zhao J, Peng BO, Qiao Z. Sequencing study on familial lung squamous cancer. Oncol Lett. 2015 Oct;10(4):2634-2638. Epub 2015 Aug 7. IF=1.554
  • Lu J, Yin J, Dong R, Yang T, Yuan L, Zang L, Xu C, Peng B, Zhao J, Du X. Targeted sequencing of cancer-associated genes in hepatocellular carcinoma using next generation sequencing. Mol Med Rep. 2015 Sep;12(3):4678-82. doi: 10.3892/mmr. 2015.3952. Epub 2015 Jun 17. IF=1.554
  • Lu M, Li J, Luo Z, Zhang S, Xue S, Wang K, Shi Y, Zhang C, Chen H, Li Z. Roles of dopamine receptors and their antagonist thioridazine in hepatoma metastasis. Onco Targets Ther. 2015 Jun 22;8:1543-52. doi: 10.2147/OTT.S77373. eCollection 2015. IF=2.311
  • Xiao X, Wang W, Zhang H, Gao P, Fan B, Huang C, Fu J, Chen G, Shi L, Zhu H, Li X, Li J, Fan H, Wu Z, Guo Z, Hu Y, Wu S, Yu X, Xu C, Wang Z. Individualized chemotherapy for osteosarcoma and identification of gene mutations in osteosarcoma. Tumour Biol. 2015 Apr; 36(4):2427-35. doi: 10.1007/s13277-014-2853-5. Epub 2014 Nov 28. IF=3.611
  1. SEQC/MAQC-III Consortium. A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium. Nat Biotechnol. 2014 Sep; 32(9):903-14. doi: 10.1038/nbt.2957. Epub 2014 Aug 24. IF=41.514
  2. Herrmann A, Cherryholmes G, Schroeder A, Phallen J, Alizadeh D, Xin H, Wang T, Lee H, Lahtz C, Swiderski P, Armstrong B, Kowolik C, Gallia GL, Lim M, Brown C, Badie B, Forman S, Kortylewski M, Jove R, Yu H. TLR9 is critical for glioma stem cell maintenance and targeting. Cancer Res. 2014 Sep 15;74(18):5218-28. doi: 10.1158/0008-5472.CAN-14-1151. Epub 2014 Jul 21. IF=9.329
  3. Yu Y, Fuscoe JC, Zhao C, Guo C, Jia M, Qing T, Bannon DI, Lancashire L, Bao W, Du T, Luo H, Su Z, Jones WD, Moland CL, Branham WS, Qian F, Ning B, Li Y, Hong H, Guo L, Mei N, Shi T, Wang KY, Wolfinger RD, Nikolsky Y, Walker SJ, Duerksen-Hughes P, Mason CE, Tong W, Thierry-Mieg J, Thierry-Mieg D, Shi L, Wang C. A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages. Nat Commun. 2014;5:3230. doi: 10.1038/ncomms4230. IF=11.47
  4. Lee H, Zhang P, Herrmann A, Yang C, Xin H, Wang Z, Hoon DS, Forman SJ, Jove R, Riggs AD, Yu H. Acetylated STAT3 is crucial for methylation of tumor-suppressor gene promoters and inhibition by resveratrol results in demethylation. Proc Natl Acad Sci U S A. 2012 May 15;109(20):7765-9. doi: 10.1073/pnas.1205132109. Epub 2012 Apr 30. IF=9.674
  5. Deng J, Liu Y, Lee H, Herrmann A, Zhang W, Zhang C, Shen S, Priceman SJ, Kujawski M, Pal SK, Raubitschek A, Hoon DS, Forman S, Figlin RA, Liu J, Jove R, Yu H. S1PR1-STAT3 signaling is crucial for myeloid cell colonization at future metastatic sites. Cancer Cell. 2012 May 15;21(5):642-54. doi: 10.1016/j.ccr.2012.03.039. IF=23.523
  6. Gongping Wang, Zhenzhen Wang, Bo Zhou, Canhui Jin, Zengfang Wang, Yantong Yang, Wei Zhang, Ye Chen, Bianhong Li, Lin Guo, Deping Han, Bo Peng, Jiangman Zhao, Chang Zhang, Xiaoshan Feng , Lu Wang. Targeted deep sequencing reveals recurrent mutations in gastric carcinomas. Accepted by Oncology Letters. IF=1.554
  7. Chunyan Zhang, Hong Xin,Wang Zhang, et al. CD5 Binds to Interleukin-6 and Induces a Feed-Forward Loop with the Transcription Factor STAT3 in B Cells to Promote Cancer. Immunity. 2016 Apr 19;44(4):913-23. doi: 10.1016/j.immuni .2016.04.003. IF=24.082
  8. He Q, Peng B, Zhuang D, Xiao L, et al. Clinicopathological significance of β -tubulin isotype III gene expression in breast cancer patients. Cancer Biomark. 2015;15(6):823-31. doi: 10.3233/CBM-150526. IF=1.736
  9. Chaoqian Liu, Yan Guo, Weiwei Wu, Zhenzhen Zhang, Lu Xu, Kainan Wu, Wei Hu, Guoping Liu, Junyi Shi, Cheng Xu, Jianwei Bi, Yuan Sheng. The plasma olfactomedin 4 level in peripheral blood and its association with clinical features of breast cancer. Accepted by Oncology Letters. IF=1.482
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